Last edition Elsevier Combining a reader-friendly textbook and a rich, full-color atlas, this bestselling resource equips medical, dental, health professions, and undergraduate biology and cell biology students with a comprehensive grasp of the clinical and functional correlates of histology and a vivid understanding of the structural and functional details of cells, tissues, and organs. Updated content throughout the text reflects the latest advances in cellular and molecular biology, accompanied by large, high-resolution illustrations and full-color photomicrographs that clarify microanatomy in vibrant detail. Ideal for integrated curriculums as well as standalone histology courses, this proven approach is accompanied by popular pedagogical features that distill complex information and help students save time.
Last Edition
ISBN 13:h9781975115364
Imprint:hLippincott Williams & Wilkins
Language:hEnglish
Authors:hWojciech Pawlina
Pub Date:h01/2019
Pages:h928
Illus:hIllustrated
Weight:h2,180.000 grams
Size:h213 X 276 mm
Product Type:hSoftcover
| List Price |
| grn 2196 |
| $ 72,00 |
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- • “Two-in-one” approach supplements clearly written chapters with dynamic atlas illustrations to enhance understanding at the point of learning.
- • Updated content equips students with the most current, clinically relevant understanding of cellular and molecular biology.
- • 435 high-resolution, full-color digital photomicrographs across more than 100 atlas plates clarify key structures.
- • Updated full-color illustrations and clinical images refine students’ understanding of microanatomy and cell and molecular biology in rich detail.
- • Updated Histology “101” Notebook reviews summarize chapter content in a concise, notebook-style format preferred by students.
- • Color-coded text highlights key terms and clinical information for fast, efficient reference.
- • Boxed “Folders” familiarize students with conditions they may encounter on rotations during clerkship.
- • Tables and bulleted text give quick access to staining techniques and other essential chapter details.
- Wojciech Pawlina , M.D. is a Professor and Chair of the Department of Anatomy at the Mayo Clinic College of Medicine in Rochester, Minnesota, USA. He serves as the Assistant Dean for Curriculum Development and Innovation at Mayo Medical School and as the Medical Director of Procedural Skills Laboratory. Dr. Pawlina teaches gross anatomy, embryology, and histology to medical students, residents, fellows, and other health care professionals. His research interest in medical education is directed towards strategies to implement professionalism, leadership, and teamwork curriculum in early medical education. Recently he was selected as the Editor-in-Chief of Anatomical Sciences Education.
- Michael H. Ross. Michael H. Ross, an eminent scholar, professor, and chairman emeritus of the Department of Anatomy and Cell Biology at the University of Florida, College of Medicine in Gainesville, passed away in Gainesville, Florida on June 8th at the age of 78.
- Preface
- • Acknowledgments
- • 1 Methods • OVERVIEW OF METHODS USED IN HISTOLOGY • TISSUE PREPARATION • Hematoxylin and Eosin Staining with Formalin Fixation • Other Fixatives
- • Folder 1.1 Clinical Correlation: Frozen Sections • Other Staining Procedures • HISTOCHEMISTRY AND CYTOCHEMISTRY • Chemical Composition of Histologic Samples • Chemical Basis of Staining • Acidic and Basic Dyes • Metachromasia • Aldehyde Groups and the Schiff Reagent
- • Folder 1.2 Functional Considerations: Feulgen Microspectrophotometry • Enzyme Digestion • Enzyme Histochemistry • Immunocytochemistry
- • Folder 1.3 Clinical Correlation: Monoclonal Antibodies in Medicine • Hybridization Techniques • Autoradiography • Expansion Microscopy • MICROSCOPY • Light Microscopy
- • Folder 1.4 Functional Considerations: Proper Use of the Light Microscope • Examination of a Histologic Slide Preparation in the Light Microscope • Other Optical Systems • Super-Resolution Microscopy • Electron Microscopy • Atomic Force Microscopy • Virtual Microscopy • HISTOLOGY 101
- • 2 Cell Cytoplasm • OVERVIEW OF THE CELL AND CYTOPLASM • MEMBRANOUS ORGANELLES • Plasma Membrane • Signaling Processes • Membrane Transport and Vesicular Transport • Endocytosis • Exocytosis • Endosomes • Lysosomes
- • Folder 2.1 Clinical Correlation: Lysosomal Storage Diseases • Autophagy • Proteasome-Mediated Degradation • Rough Endoplasmic Reticulum • Smooth Endoplasmic Reticulum • Golgi Apparatus • Mitochondria • Peroxisomes (Microbodies) • NONMEMBRANOUS ORGANELLES • Microtubules • Actin Filaments • Intermediate Filaments • Centrioles and Microtubule-Organizing Centers
- • Folder 2.2 Clinical Correlation: Abnormalities in Microtubules and Filaments • Basal Bodies • INCLUSIONS
- • Folder 2.3 Clinical Correlation: Abnormal Duplication of Centrioles and Cancer • CYTOPLASMIC MATRIX • HISTOLOGY 101
- • 3 The Cell Nucleus • OVERVIEW OF THE NUCLEUS • NUCLEAR COMPONENTS • Chromatin • Nucleolus
- • Folder 3.1 Clinical Correlation: Cytogenetic Testing
- • Folder 3.2 Clinical Correlation: Regulation of Cell Cycle and Cancer Treatment • Nuclear Envelope • Nucleoplasm • CELL RENEWAL • CELL CYCLE • Phases and Checkpoints Within the Cell Cycle • Regulation of the Cell Cycle • Mitosis • Meiosis • Prophase I • Metaphase I • Anaphase I and Telophase I • Meiosis II • CELL DEATH • Apoptosis • Other Forms of Programmed Cell Death • HISTOLOGY 101
- • 4 Tissues: Concept and Classification • OVERVIEW OF TISSUES • EPITHELIUM • CONNECTIVE TISSUE • MUSCLE TISSUE • NERVE TISSUE • HISTOGENESIS OF TISSUES • Ectodermal Derivatives • Mesodermal Derivatives • Endodermal Derivatives
- • Folder 4.1 Clinical Correlation: Ovarian Teratomas • IDENTIFYING TISSUES • HISTOLOGY 101
- • 5 Epithelial Tissue • OVERVIEW OF EPITHELIAL STRUCTURE AND FUNCTION • CLASSIFICATION OF EPITHELIUM • CELL POLARITY • THE APICAL DOMAIN AND ITS MODIFICATIONS
- • Folder 5.1 Clinical Correlation: Epithelial Metaplasia • Microvilli • Stereocilia • Cilia
- • Folder 5.2 Clinical Correlation: Primary Ciliary Dyskinesia (Immotile Cilia Syndrome) • THE LATERAL DOMAIN AND ITS SPECIALIZATIONS IN CELL-TO-CELL ADHESION • Occluding Junctions • Anchoring Junctions
- • Folder 5.3 Clinical Correlation: Junctional Complexes as a Target of Pathogenic Agents • Communicating Junctions • Morphologic Modifications of the Lateral Cell Surface • THE BASAL DOMAIN AND ITS SPECIALIZATIONS IN CELL-TO-EXTRACELLULAR MATRIX ADHESION • Basement Membrane Structure and Function
- • Folder 5.4 Functional Considerations: Basement Membrane and Basal Lamina Terminology • Cell-to-Extracellular Matrix Junctions • Morphologic Modifications of the Basal Cell Surface • GLANDS • EPITHELIAL CELL RENEWAL
- • Folder 5.5 Functional Considerations: Mucous and Serous Membranes • HISTOLOGY 101 • PLATE 1 Simple Squamous and Cuboidal Epithelia • PLATE 2 Simple and Stratified Epithelia • PLATE 3 Stratified Epithelia and Epithelioid Tissues
- • 6 Connective Tissue • OVERVIEW OF CONNECTIVE TISSUE • EMBRYONIC CONNECTIVE TISSUE • CONNECTIVE TISSUE PROPER • CONNECTIVE TISSUE FIBERS • Collagen Fibers and Fibrils • Biosynthesis and Degradation of Collagen Fibers
- • Folder 6.1 Clinical Correlation: Collagenopathies • Reticular Fibers • Elastic Fibers
- • Folder 6.2 Clinical Correlation: Sun Exposure and Molecular Changes in Photoaged Skin • EXTRACELLULAR MATRIX • CONNECTIVE TISSUE CELLS • Fibroblasts and Myofibroblasts • Macrophages • Mast Cells
- • Folder 6.3 Clinical Correlation: Role of Myofibroblasts in Wound Repair
- • Folder 6.4 Functional Considerations: The Mononuclear Phagocyte System • Basophils
- • Folder 6.5 Clinical Correlation: The Role of Mast Cells and Basophils in Allergic Reactions • Adipocytes • Adult Stem Cells and Pericytes • Lymphocytes, Plasma Cells, and Other Cells of the Immune System • HISTOLOGY 101 • PLATE 4 Loose and Dense Irregular Connective Tissue • PLATE 5 Dense Regular Connective Tissue, Tendons, and Ligaments • PLATE 6 Elastic Fibers and Elastic Lamellae
- • 7 Cartilage • OVERVIEW OF CARTILAGE • HYALINE CARTILAGE
- • Folder 7.1 Clinical Correlation: Osteoarthritis • ELASTIC CARTILAGE • FIBROCARTILAGE • CHONDROGENESIS AND CARTILAGE GROWTH
- • Folder 7.2 Clinical Correlation: Malignant Tumors of the Cartilage: Chondrosarcomas • REPAIR OF HYALINE CARTILAGE • HISTOLOGY 101 • PLATE 7 Hyaline Cartilage • PLATE 8 Hyaline Cartilage and the Developing Skeleton • PLATE 9 Elastic Cartilage • PLATE 10 Fibrocartilage
- • 8 Bone • OVERVIEW OF BONE • GENERAL STRUCTURE OF BONES • Bone as an Organ • Outer Surface of Bones
- • Folder 8.1 Clinical Correlation: Joint Diseases • Bone Cavities • TYPES OF BONE TISSUE • Mature Bone • Immature Bone • CELLS OF BONE TISSUE • Osteoprogenitor Cells • Osteoblasts • Osteocytes • Bone-Lining Cells • Osteoclasts
- • Folder 8.2 Clinical Correlation: Osteoporosis • BONE FORMATION • Intramembranous Ossification • Endochondral Ossification • Growth of Endochondral Bone • Development of the Osteonal (Haversian) System • BIOLOGIC MINERALIZATION AND MATRIX VESICLES • BONE AS A TARGET OF ENDOCRINE HORMONES AND AS AN ENDOCRINE ORGAN
- • Folder 8.3 Clinical Correlation: Nutritional Factors in Bone Formation
- • Folder 8.4 Functional Considerations: Hormonal Regulation of Bone Growth • BIOLOGY OF BONE REPAIR • HISTOLOGY 101 • PLATE 11 Bone, Ground Section • PLATE 12 Bone and Bone Tissue • PLATE 13 Endochondral Bone Formation I • PLATE 14 Endochondral Bone Formation II • PLATE 15 Intramembranous Bone Formation
- • 9 Adipose Tissue • OVERVIEW OF ADIPOSE TISSUE • WHITE ADIPOSE TISSUE • Function of White Adipose Tissue
- • Folder 9.1 Clinical Correlation: Obesity • Differentiation of Adipocytes • Structure of Adipocytes and Adipose Tissue • Regulation of Adipose Tissue • BROWN ADIPOSE TISSUE
- • Folder 9.2 Clinical Correlation: Adipose Tissue Tumors
- • Folder 9.3 Clinical Correlation: PET Scanning and Brown Adipose Tissue Interference • TRANSDIFFERENTIATION OF ADIPOSE TISSUE • HISTOLOGY 101 • PLATE 16 Adipose Tissue
- • 10 Blood • OVERVIEW OF BLOOD • PLASMA • ERYTHROCYTES
- • Folder 10.1 Clinical Correlation: ABO and Rh Blood Group Systems
- • Folder 10.2 Clinical Correlation: Hemoglobin in Patients with Diabetes
- • Folder 10.3 Clinical Correlation: Hemoglobin Disorders • LEUKOCYTES • Neutrophils
- • Folder 10.4 Clinical Correlation: Inherited Disorders of Neutrophils; Chronic Granulomatous Disease • Eosinophils
- • Folder 10.5 Clinical Correlation: Hemoglobin Breakdown and Jaundice • Basophils • Lymphocytes • Monocytes • THROMBOCYTES • COMPLETE BLOOD COUNT • FORMATION OF BLOOD CELLS (HEMOPOIESIS) • Monophyletic Theory of Hemopoiesis • Development of Erythrocytes (Erythropoiesis) • Kinetics of Erythropoiesis • Development of Thrombocytes (Thrombopoiesis) • Development of Granulocytes (Granulopoiesis) • Kinetics of Granulopoiesis • Development of Monocytes • Development of Lymphocytes (Lymphopoiesis) • BONE MARROW
- • Folder 10.6 Clinical Correlation: Cellularity of the Bone Marrow • HISTOLOGY 101 • PLATE 17 Erythrocytes and Granulocytes • PLATE 18 Agranulocytes and Red Marrow • PLATE 19 Erythropoiesis • PLATE 20 Granulopoiesis
- • 11 Muscle Tissue • OVERVIEW AND CLASSIFICATION OF MUSCLE • SKELETAL MUSCLE • Myofibrils and Myofilaments
- • Folder 11.1 Functional Considerations: Muscle Metabolism and Ischemia
- • Folder 11.2 Clinical Correlation: Muscular Dystrophies—Dystrophin and Dystrophin-Associated Proteins • The Actomyosin Cross-Bridge Cycle • Regulation of Muscle Contraction • Motor Innervation
- • Folder 11.3 Clinical Correlation: Myasthenia Gravis • Sensory Innervation • Development, Repair, Healing, and Renewal • CARDIAC MUSCLE • Structure of Cardiac Muscle • Injury and Repair • SMOOTH MUSCLE • Structure of Smooth Muscle • Functional Aspects of Smooth Muscle • Renewal, Repair, and Differentiation
- • Folder 11.4 Functional Considerations: Comparison of the Three Muscle Types • HISTOLOGY 101 • PLATE 21 Skeletal Muscle I • PLATE 22 Skeletal Muscle II and Electron Microscopy • PLATE 23 Myotendinous Junction • PLATE 24 Cardiac Muscle • PLATE 25 Cardiac Muscle, Purkinje Fibers • PLATE 26 Smooth Muscle
- • 12 Nerve Tissue • OVERVIEW OF THE NERVOUS SYSTEM • COMPOSITION OF NERVE TISSUE • THE NEURON • Cell Body • Dendrites and Axons • Neuronal Transport Systems • Synapses
- • Folder 12.1 Clinical Correlation: Parkinson Disease • Synaptic Transmission • Neurotransmitters • SUPPORTING CELLS OF THE NERVOUS SYSTEM: THE NEUROGLIA • Peripheral Neuroglia • Schwann Cells and the Myelin Sheath
- • Folder 12.2 Clinical Correlation: Demyelinating Diseases • Satellite Cells • Enteric Neuroglial Cells • Central Neuroglia • Impulse Conduction • ORIGIN OF NERVE TISSUE CELLS • ORGANIZATION OF THE PERIPHERAL NERVOUS SYSTEM • Peripheral Nerves • Connective Tissue Components of a Peripheral Nerve • Afferent (Sensory) Receptors • ORGANIZATION OF THE AUTONOMIC NERVOUS SYSTEM • Sympathetic and Parasympathetic Divisions of the Autonomic Nervous System • Enteric Division of the Autonomic Nervous System • A Summarized View of Autonomic Distribution • Head • Thorax • Abdomen and Pelvis • Extremities and Body Wall • ORGANIZATION OF THE CENTRAL NERVOUS SYSTEM • Cells of the Gray Matter • Organization of the Spinal Cord • Connective Tissue of the Central Nervous System • Blood–Brain Barrier • RESPONSE OF NEURONS TO INJURY • Degeneration
- • Folder 12.3 Clinical Correlation: Reactive Gliosis: Scar Formation in the Central Nervous System • Regeneration • HISTOLOGY 101 • PLATE 27 Sympathetic and Dorsal Root Ganglia • PLATE 28 Peripheral Nerve • PLATE 29 Cerebrum • PLATE 30 Cerebellum • PLATE 31 Spinal Cord
- • 13 Cardiovascular System • OVERVIEW OF THE CARDIOVASCULAR SYSTEM • HEART • Wall of the Heart • Heart Valves • Intrinsic Regulation of Heart Rate • Systemic Regulation of Heart Function • GENERAL FEATURES OF ARTERIES AND VEINS • Layers of Vascular Wall • Vascular Endothelium
- • Folder 13.1 Clinical Correlation: Atherosclerosis
- • Folder 13.2 Clinical Correlation: Hypertension • ARTERIES • Large Arteries (Elastic Arteries) • Medium Arteries (Muscular Arteries) • Small Arteries and Arterioles • CAPILLARIES • Classification of Capillaries • Functional Aspects of Capillaries • ARTERIOVENOUS SHUNTS • VEINS • Venules and Small Veins • Medium Veins • Large Veins • ATYPICAL BLOOD VESSELS
- • Folder 13.3 Clinical Correlation: Coronary Heart Disease • LYMPHATIC VESSELS • HISTOLOGY 101 • PLATE 32 Heart • PLATE 33 Aorta • PLATE 34 Muscular Arteries and Medium Veins • PLATE 35 Arterioles, Venules, and Lymphatic Vessels
- • 14 Immune System and Lymphatic Tissues and Organs • OVERVIEW OF THE IMMUNE AND LYMPHATIC SYSTEMS • CELLS OF THE IMMUNE SYSTEM • Overview • Lymphocytes
- • Folder 14.1 Functional Considerations: Origin of the Names T Lymphocyte and B Lymphocyte • Lymphocyte Development and Differentiation • Immune Responses to Antigens
- • Folder 14.2 Clinical Correlation: Hypersensitivity Reactions • Activation of T and B Cells • Antigen-Presenting Cells • LYMPHATIC TISSUES AND ORGANS • Lymphatic Vessels
- • Folder 14.3 Clinical Correlation: Human Immunodeficiency Virus (HIV) and Acquired Immunodeficiency Syndrome (AIDS) • Diffuse Lymphatic Tissue and Lymphatic Nodules • Lymph Nodes • Cells of the Reticular Meshwork • General Architecture of the Lymph Node
- • Folder 14.4 Clinical Correlation: Reactive (Inflammatory) Lymphadenitis • Thymus • General Architecture of the Thymus • Blood–Thymus Barrier and Thymic-Cell Education • Spleen • Blood Circulation in Spleen • HISTOLOGY 101 • PLATE 36 Palatine Tonsil • PLATE 37 Lymph Node I • PLATE 38 Lymph Node II • PLATE 39 Spleen I • PLATE 40 Spleen II • PLATE 41 Thymus
- • 15 Integumentary System • OVERVIEW OF THE INTEGUMENTARY SYSTEM • LAYERS OF THE SKIN • Epidermis • Dermis
- • Folder 15.1 Clinical Correlation: Cancers of Epidermal Origin • CELLS OF THE EPIDERMIS • Keratinocytes • Melanocytes • Langerhans Cells • Merkel’s Cells • STRUCTURES OF SKIN • Nerve Supply
- • Folder 15.2 Clinical Correlation: Mohs Micrographic Surgery • Epidermal Skin Appendages • Hair Follicles and Hair
- • Folder 15.3 Functional Considerations: Skin Color
- • Folder 15.4 Functional Considerations: Hair Growth and Hair Characteristics • Sebaceous Glands
- • Folder 15.5 Clinical Correlation: Sweating and Disease • Sweat Glands • Eccrine Sweat Glands • Apocrine Sweat Glands • Nails
- • Folder 15.6 Clinical Correlation: Skin Repair • HISTOLOGY 101 • PLATE 42 Skin I • PLATE 43 Skin II • PLATE 44 Apocrine and Eccrine Sweat Glands • PLATE 45 Sweat and Sebaceous Glands • PLATE 46 Integument and Sensory Organs • PLATE 47 Hair Follicle and Nail
- • 16 Digestive System I: Oral Cavity and Associated Structures • OVERVIEW OF THE DIGESTIVE SYSTEM • ORAL CAVITY • TONGUE
- • Folder 16.1 Clinical Correlation: The Genetic Basis of Taste • TEETH AND SUPPORTING TISSUES
- • Folder 16.2 Clinical Correlation: Classification of Permanent (Secondary) and Deciduous (Primary) Dentition • Enamel • Cementum • Dentin • Dental Pulp and Central Pulp Cavity (Pulp Chamber) • Supporting Tissues of the Teeth • SALIVARY GLANDS • Secretory Gland Acini
- • Folder 16.3 Clinical Correlation: Dental Caries • Salivary Ducts • Major Salivary Glands • Parotid Gland • Submandibular Gland • Sublingual Gland • Saliva
- • Folder 16.4 Clinical Correlation: Salivary Gland Tumors • HISTOLOGY 101 • PLATE 48 Lip and Mucocutaneous Junction • PLATE 49 Tongue I • PLATE 50 Tongue II—Foliate Papillae and Taste Buds • PLATE 51 Submandibular Gland • PLATE 52 Parotid Gland • PLATE 53 Sublingual Gland
- • 17 Digestive System II: Esophagus and Gastrointestinal Tract • OVERVIEW OF THE ESOPHAGUS AND GASTROINTESTINAL TRACT • Mucosa • Submucosa • Muscularis Externa • Serosa and Adventitia • ESOPHAGUS • STOMACH • Gastric Mucosa • Fundic Glands of the Gastric Mucosa
- • Folder 17.1 Clinical Correlation: Pernicious Anemia and Peptic Ulcer Disease
- • Folder 17.2 Clinical Correlation: Zollinger-Ellison Syndrome
- • Folder 17.3 Functional Considerations: The Gastrointestinal Endocrine System • Cardiac Glands of the Gastric Mucosa • Pyloric Glands of the Gastric Mucosa • Epithelial Cell Renewal in the Stomach • Lamina Propria and Muscularis Mucosae • Gastric Submucosa • Gastric Muscularis Externa • Gastric Serosa • SMALL INTESTINE
- • Folder 17.4 Functional Considerations: Digestive and Absorptive Functions of Enterocytes
- • Folder 17.5 Functional Considerations: Immune Functions of the Alimentary Canal • Submucosa • Muscularis Externa • Serosa • Epithelial Cell Renewal in the Small Intestine • LARGE INTESTINE • Mucosa • Epithelial Cell Renewal in the Large Intestine • Lamina Propria
- • Folder 17.6 Clinical Correlation: The Pattern of Lymph Vessel Distribution and Diseases of the Large Intestine • Muscularis Externa • Submucosa and Serosa • Cecum and Appendix • Rectum and Anal Canal
- • Folder 17.7 Clinical Correlation: Colorectal Cancer • HISTOLOGY 101 • PLATE 54 Esophagus • PLATE 55 Esophagus and Stomach, Cardiac Region • PLATE 56 Stomach I • PLATE 57 Stomach II • PLATE 58 Gastroduodenal Junction • PLATE 59 Duodenum • PLATE 60 Jejunum • PLATE 61 Ileum • PLATE 62 Colon • PLATE 63 Appendix • PLATE 64 Anal Canal
- • 18 Digestive System III: Liver, Gallbladder, and Pancreas • LIVER • Overview • Liver Physiology • Folder 18.1 Clinical Correlation: Lipoproteins • Blood Supply to the Liver • Structural Organization of the Liver • Liver Lobules • Blood Vessels of the Parenchyma
- • Folder 18.2 Clinical Correlation: Congestive Heart Failure, Acetaminophen Overdose, and Liver Necrosis • Perisinusoidal Space (Space of Disse) • Lymphatic Pathway • Hepatocytes • Biliary Tree • GALLBLADDER • PANCREAS • Overview • Exocrine Pancreas • Duct System of the Exocrine Pancreas • Endocrine Pancreas • Functions of Pancreatic Hormones
- • Folder 18.3 Clinical Correlation: Insulin Production and Alzheimer Disease • Regulation of Islet Activity
- • Folder 18.4 Functional Considerations: Insulin Synthesis, an Example of Posttranslational Processing • HISTOLOGY 101 • PLATE 65 Liver I • PLATE 66 Liver II • PLATE 67 Gallbladder • PLATE 68 Pancreas
- • 19 Respiratory System • OVERVIEW OF THE RESPIRATORY SYSTEM • NASAL CAVITIES • Vestibule of the Nasal Cavity • Respiratory Region of the Nasal Cavity • Olfactory Region of the Nasal Cavity • Paranasal Sinuses • PHARYNX • LARYNX • TRACHEA
- • Folder 19.1 Clinical Correlation: Common Conditions Affecting the Nasal Mucosa • Tracheal Epithelium • Basement Membrane, Lamina Propria, and Submucosa • BRONCHI • BRONCHIOLES • Bronchiolar Structure • Bronchiolar Function
- • Folder 19.2 Clinical Correlation: Squamous Metaplasia in the Respiratory Tract
- • Folder 19.3 Clinical Correlation: Asthma • ALVEOLI • BLOOD SUPPLY • LYMPHATIC VESSELS • NERVES
- • Folder 19.4 Clinical Correlation: Cystic Fibrosis
- • Folder 19.5 Clinical Correlation: Chronic Obstructive Pulmonary Disease and Pneumonia • HISTOLOGY 101 • PLATE 69 Olfactory Mucosa • PLATE 70 Larynx • PLATE 71 Trachea • PLATE 72 Bronchioles and End Respiratory Passages • PLATE 73 Terminal Bronchiole, Respiratory Bronchiole, and Alveolus
- • 20 Urinary System • OVERVIEW OF THE URINARY SYSTEM
- • Folder 20.1 Functional Considerations: Kidney and Vitamin D • GENERAL STRUCTURE OF THE KIDNEY • Capsule • Cortex and Medulla • Kidney Lobes and Lobules • The Nephron • General Organization of the Nephron • Tubules of the Nephron • Types of Nephrons • Collecting Ducts • Filtration Apparatus of the Kidney
- • Folder 20.2 Clinical Correlation: Antiglomerular Basement Membrane Antibody-Induced Glomerulonephritis; Goodpasture Syndrome • Mesangium • Juxtaglomerular Apparatus
- • Folder 20.3 Clinical Correlation: Renin–Angiotensin–Aldosterone System and Hypertension • KIDNEY TUBULE FUNCTION • Proximal Convoluted Tubule • Proximal Straight Tubule • Thin Segment of Loop of Henle
- • Folder 20.4 Clinical Correlation: Examination of the Urine—Urinalysis • Distal Straight Tubule • Distal Convoluted Tubule • Connecting Tubule • Cortical and Medullary Collecting Ducts
- • Folder 20.5 Functional Considerations: Structure and Function of Aquaporin Water Channels • INTERSTITIAL CELLS • HISTOPHYSIOLOGY OF THE KIDNEY
- • Folder 20.6 Functional Considerations: Antidiuretic Hormone Regulation of Collecting Duct Function • BLOOD SUPPLY • LYMPHATIC VESSELS • NERVE SUPPLY • URETER, URINARY BLADDER, AND URETHRA • Ureters • Urinary Bladder • Urethra • HISTOLOGY 101 • PLATE 74 Kidney I • PLATE 75 Kidney II • PLATE 76 Kidney III • PLATE 77 Kidney IV • PLATE 78 Ureter • PLATE 79 Urinary Bladder
- • 21 Endocrine Organs • OVERVIEW OF THE ENDOCRINE SYSTEM • Hormones and Their Receptors • Regulation of Hormone Secretion and Feedback Mechanism
- • Folder 21.1 Functional Considerations: Regulation of Pituitary Gland Secretion • PITUITARY GLAND (HYPOPHYSIS) • Gross Structure and Development • Blood Supply • Nerve Supply • Anterior Lobe of the Pituitary Gland (Adenohypophysis) • Pars Distalis • Pars Intermedia • Pars Tuberalis • Posterior Lobe of the Pituitary Gland (Neurohypophysis)
- • Folder 21.2 Clinical Correlation: Principles of Endocrine Diseases
- • Folder 21.3 Clinical Correlation: Pathologies Associated with Antidiuretic Hormone Secretion • HYPOTHALAMUS • PINEAL GLAND • THYROID GLAND
- • Folder 21.4 Clinical Correlation: Abnormal Thyroid Function • PARATHYROID GLANDS • ADRENAL GLANDS • Blood Supply • Cells of the Adrenal Medulla
- • Folder 21.5 Clinical Correlation: Chromaffin Cells and Pheochromocytoma • Zonation of the Adrenal Cortex • Zona Glomerulosa • Zona Fasciculata • Zona Reticularis • Fetal Adrenal Gland
- • Folder 21.6 Functional Considerations: Biosynthesis of Adrenal Hormones • HISTOLOGY 101 • PLATE 80 Pituitary I • PLATE 81 Pituitary II • PLATE 82 Pineal Gland • PLATE 83 Parathyroid and Thyroid Glands • PLATE 84 Adrenal Gland I • PLATE 85 Adrenal Gland II
- • 22 Male Reproductive System • OVERVIEW OF THE MALE REPRODUCTIVE SYSTEM • TESTIS • Sex Determination and Development of the Testis
- • Folder 22.1 Functional Considerations: Hormonal Regulation of Spermatogenesis
- • Folder 22.2 Clinical Correlation: Factors Affecting Spermatogenesis • Structure of the Testis • Leydig Cells • SPERMATOGENESIS • Spermatogonial Phase • Spermatocyte Phase (Meiosis) • Spermatid Phase (Spermiogenesis) • Golgi Phase • Cap Phase • Acrosome Phase • Maturation Phase • Structure of the Mature Sperm • SEMINIFEROUS TUBULES • Cycle of the Seminiferous Epithelium • Waves of the Seminiferous Epithelium • Sertoli Cells
- • Folder 22.3 Clinical Correlation: Sperm-Specific Antigens and the Immune Response • INTRATESTICULAR DUCTS • EXCURRENT DUCT SYSTEM • Epididymis • Ductus Deferens • ACCESSORY SEX GLANDS • PROSTATE GLAND
- • Folder 22.4 Clinical Correlation: Benign Prostatic Hypertrophy and Cancer of the Prostate • Bulbourethral Glands • SEMEN • PENIS
- • Folder 22.5 Clinical Correlation: Mechanism of Erection and Erectile Dysfunction • HISTOLOGY 101 • PLATE 86 Testis I • PLATE 87 Testis II • PLATE 88 Efferent Ductules and Epididymis • PLATE 89 Spermatic Cord and Ductus Deferens • PLATE 90 Prostate Gland • PLATE 91 Seminal Vesicle
- • 23 Female Reproductive System • OVERVIEW OF THE FEMALE REPRODUCTIVE SYSTEM • OVARY • Ovarian Structure • Follicle Development
- • Folder 23.1 Clinical Correlation: Polycystic Ovary Disease • Ovulation • Corpus Luteum • Capacitation and Fertilization • Atresia
- • Folder 23.2 Clinical Correlation: In Vitro Fertilization • Blood Supply and Lymphatics • Innervation • UTERINE TUBES • UTERUS
- • Folder 23.3 Functional Considerations: Summary of Hormonal Regulation of the Ovarian Cycle • Cyclic Changes during the Menstrual Cycle • Implantation • Cervix • PLACENTA
- • Folder 23.4 Clinical Correlation: The Placenta • VAGINA • EXTERNAL GENITALIA
- • Folder 23.5 Clinical Correlation: Cervical Cytology: The Pap Test • MAMMARY GLANDS • Hormonal Regulation of the Mammary Gland
- • Folder 23.6 Clinical Correlation: Cervical Cancer and Human Papillomavirus Infections
- • Folder 23.7 Functional Considerations: Lactation and Infertility • Involution of the Mammary Gland • Blood Supply and Lymphatics • Innervation • HISTOLOGY 101 • PLATE 92 Ovary I • PLATE 93 Ovary II • PLATE 94 Corpus Luteum • PLATE 95 Uterine Tube • PLATE 96 Uterus I • PLATE 97 Uterus II • PLATE 98 Cervix • PLATE 99 Placenta I • PLATE 100 Placenta II • PLATE 101 Vagina • PLATE 102 Mammary Gland Inactive Stage • PLATE 103 Mammary Gland, Late Proliferative and Lactating Stages
- • 24 Eye • OVERVIEW OF THE EYE • GENERAL STRUCTURE OF THE EYE • Layers of the Eye • Chambers of the Eye • Development of the Eye • MICROSCOPIC STRUCTURE OF THE EYE • Corneoscleral Coat
- • Folder 24.1 Clinical Correlation: Glaucoma • Vascular Coat (Uvea)
- • Folder 24.2 Clinical Correlation: Retinal Detachment
- • Folder 24.3 Clinical Correlation: Age-Related Macular Degeneration • Retina • Layers of the Retina
- • Folder 24.4 Clinical Correlation: Clinical Imaging of the Retina
- • Folder 24.5 Clinical Correlation: Color Blindness • Specialized Regions of the Retina • Vessels of the Retina • Crystalline Lens • Vitreous Body • ACCESSORY STRUCTURES OF THE EYE
- • Folder 24.6 Clinical Correlation: Conjunctivitis • HISTOLOGY 101 • PLATE 104 Eye I • PLATE 105 Eye II: Retina • PLATE 106 Eye III: Anterior Segment • PLATE 107 Eye IV: Sclera, Cornea, and Lens
- • 25 Ear • OVERVIEW OF THE EAR • EXTERNAL EAR • MIDDLE EAR
- • Folder 25.1 Clinical Correlation: Otosclerosis
- • Folder 25.2 Clinical Correlation: Hearing Loss—Vestibular Dysfunction • INTERNAL EAR • Structures of the Bony Labyrinth • Structures of the Membranous Labyrinth • Sensory Cells of the Membranous Labyrinth • Sensory Receptors of the Membranous Labyrinth • Sound Perception • Innervation of the Internal Ear
- • Folder 25.3 Clinical Correlation: Vertigo • Blood Vessels of the Membranous Labyrinth • HISTOLOGY 101 • PLATE 108 Ear • PLATE 109 Cochlear Canal and Organ of Corti • Index
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- Delivery is carried out anywhere in Ukraine.
- Delivery time 1-2 days, if the book is available and 3-4 weeks, if it is necessary to order from the publisher.