Last edition Elsevier Find what you need to know—fast! This bestselling volume in the popular Step-Up series provides a high-yield review of medicine, ideal for preparing for clerkships or clinical rotations, shelf exams, and the USMLE Step 2. Clinical pearls, full-color illustrations, and “Quick Hits” provide essential information in an efficient, easy-to-remember manner to help you excel on your exams and succeed in the clinical setting. Also includes a 100-question practice exam to support preparation.
Last Edition
ISBN 13:h9781975139025
Imprint:hLWW
Language:hEnglish
Authors:hSteven Agabegi
Pub Date:h05/2019
Pages:h592
Illus:hIllustrated
Weight:h550.000 grams
Size:h208 X 284 mm
Product Type:hSoftcover
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| grn 1854 |
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- • Updated and revised content reflects extensive research with faculty and students.
- • Figures, charts, tables, graphs, and mnemonics aid visual learners and facilitate retention of essential material.
- • Enhanced high-yield outline format and Quick Hits save time and help students review more efficiently.
- • 100-question practice exam helps students prepare for shelf and board.
- • Succinct, outline approach keeps “extra” material to a minimum, focusing on the core content students need to know.
- • Clinical pearls help students “file away” clinical connections for handy retrieval at test time and aid in the transition from basic science to clinical medicine.
- • Easy-to-follow algorithms demonstrate examples of effective clinical reasoning, particularly for similar complaints.
- • Coverage includes every essential area of medicine, including body system diseases and disorders; fluids, electrolytes, and acid-base disorders; hematologic diseases and neoplasms; infectious diseases; diseases of the skin and hypersensitivity disorders; and ambulatory medicine.
- • Helpful appendices cover radiographic and electrocardiogram interpretation, physical examination pearls, workup and management of common problems on the wards, basic statistics and evidence-based medicine, and end-of-life issues and informed consent.
- Steven S. Agabegi. Steven S. Agabegi is currently an Assistant Professor in the Department of Orthopaedic Surgery and Sports Medicine, Division of Spine Surgery, at the University of Cincinnati College of Medicine. He joined UC Health in 2009. ... Agabegi received his undergraduate and medical degree from Temple University in Philadelphia.
- • Cover • Title Page • Copyright • Advisory Board • Reviewers • Preface • Contents
- • 1 DISEASES OF THE CARDIOVASCULAR SYSTEM • Ischemic Heart Disease • Stable Angina Pectoris • Unstable Angina Pectoris • Variant (Prinzmetal) Angina • Myocardial Infarction • Chest Pain • Congestive Heart Failure • Acute Decompensated Heart Failure • Arrhythmias • Premature Complexes • Tachyarrhythmias • Atrial Fibrillation • Atrial Flutter • Multifocal Atrial Tachycardia • Paroxysmal Supraventricular Tachycardia • Wolff–Parkinson–White (WPW) Syndrome • Ventricular Tachycardia • Ventricular Fibrillation • Bradyarrhythmias • Sinus Bradycardia • Sick Sinus Syndrome • AV Block • Diseases of the Heart Muscle • Dilated Cardiomyopathy • Hypertrophic Cardiomyopathy • Restrictive Cardiomyopathy • Myocarditis • Pericardial Diseases • Acute Pericarditis • Constrictive Pericarditis • Pericardial Effusion • Cardiac Tamponade • Valvular Heart Disease • Mitral Stenosis • Aortic Stenosis • Aortic Regurgitation • Mitral Regurgitation • Tricuspid Regurgitation • Mitral Valve Prolapse • Rheumatic Heart Disease • Infective Endocarditis • Nonbacterial Thrombotic Endocarditis (Marantic Endocarditis) • Nonbacterial Verrucous Endocarditis (Libman–Sacks Endocarditis) • Congenital Heart Diseases • Atrial Septal Defect • Ventricular Septal Defect • Coarctation of the Aorta • Patent Ductus Arteriosus • Tetralogy of Fallot • Diseases of the Vasculature • Hypertensive Emergency • Aortic Dissection • Abdominal Aortic Aneurysm • Peripheral Arterial Disease (Chronic Arterial Insufficiency) • Acute Arterial Occlusion • Cholesterol Embolization Syndrome • Mycotic Aneurysm • Luetic Heart • Deep Venous Thrombosis • Chronic Venous Insufficiency (Venous Stasis Disease) • Superficial Thrombophlebitis • Cardiac Neoplasms • Atrial Myxoma • Shock • Basics of Shock • Cardiogenic Shock • Hypovolemic Shock • Septic Shock • Neurogenic Shock • Obstructive Shock
- • 2 DISEASES OF THE PULMONARY SYSTEM • Obstructive Lung Diseases • Chronic Obstructive Pulmonary Disease • Asthma • Bronchiectasis • Cystic Fibrosis • Lung Neoplasms • Lung Cancer • Solitary Pulmonary Nodule • Mediastinal Masses • Diseases of the Pleura • Pleural Effusion • Empyema • Pneumothorax • Tension Pneumothorax • Malignant Mesothelioma • Interstitial Lung Disease • Overview • Interstitial Lung Diseases Associated With Granulomas • Environmental Lung Disease/Pneumoconiosis • Interstitial Lung Disease Associated With Hypersensitivity • Alveolar Filling Disease • Miscellaneous Interstitial Lung Diseases • Respiratory Failure • Acute Respiratory Failure • Acute Respiratory Distress Syndrome • Mechanical Ventilation • Diseases of the Pulmonary Vasculature • Pulmonary Hypertension • Cor Pulmonale • Pulmonary Embolism • Miscellaneous Topics • Pulmonary Aspiration • Dyspnea • Hemoptysis
- • 3 DISEASES OF THE GASTROINTESTINAL SYSTEM • Diseases of the Colon • Colorectal Cancer • Colonic Polyps • Diverticulosis • Angiodysplasia of the Colon (Arteriovenous Malformations, Vascular Ectasia) • Acute Mesenteric Ischemia • Chronic Mesenteric Ischemia • Ogilvie Syndrome • Colonic Volvulus • Diseases of the Liver • Acute Liver Failure • Cirrhosis • Wilson Disease • Hemochromatosis • Hepatocellular Adenoma • Cavernous Hemangiomas • Focal Nodular Hyperplasia • Hepatocellular Carcinoma (Malignant Hepatoma) • Nonalcoholic Steatohepatitis • Hemobilia • Liver Cysts • Liver Abscess • Budd–Chiari Syndrome • Jaundice • Liver Function Tests • Diseases of the Gallbladder and Biliary Tract • Cholelithiasis • Acute Cholecystitis • Acalculous Cholecystitis • Choledocholithiasis • Cholangitis • Carcinoma of the Gallbladder • Primary Sclerosing Cholangitis • Primary Biliary Cholangitis • Cholangiocarcinoma • Choledochal Cysts • Bile Duct Stricture • Biliary Dyskinesia • Diseases of the Appendix • Acute Appendicitis • Carcinoid Tumors and Carcinoid Syndrome • Diseases of the Pancreas • Acute Pancreatitis • Chronic Pancreatitis • Pancreatic Cancer • Gastrointestinal Bleeding • Diseases of the Esophagus • Esophageal Cancer • Achalasia • Diffuse Esophageal Spasm • Esophageal Hiatal Hernias • Mallory–Weiss Syndrome • Plummer–Vinson Syndrome (Upper Esophageal Webs) • Schatzki Ring (Distal Esophageal Webs) • Esophageal Diverticula • Esophageal Perforation • Diseases of the Stomach • Peptic Ulcer Disease • Acute Gastritis • Chronic Gastritis • Gastric Cancer • Gastric Lymphoma • Diseases of the Small Intestine • Small Bowel Obstruction • Paralytic Ileus • Celiac Sprue • Whipple Disease • Tropical Sprue • Inflammatory Bowel Disease • Crohn Disease (“Regional Enteritis”) • Ulcerative Colitis
- • 4 ENDOCRINE AND METABOLIC DISEASES • Diseases of the Pancreas • Diabetes Mellitus • Chronic Complications of Diabetes Mellitus • Acute Complications of Diabetes Mellitus • Obesity • Hypoglycemia • Insulinoma • Zollinger–Ellison Syndrome (ZES, Gastrinoma) • Glucagonoma • Somatostatinoma • VIPoma (Verner–Morrison or Watery Diarrhea, Hypokalemia, Achlorhydria Syndrome) • Diseases of the Thyroid Gland • Hyperthyroidism • Thyroid Storm • Hypothyroidism • Thyroiditis • Thyroid Nodules • Thyroid Cancer • Diseases of the Pituitary Gland • Pituitary Adenomas • Hyperprolactinemia • Acromegaly • Craniopharyngioma • Hypopituitarism • Diabetes Insipidus • Syndrome of Inappropriate Secretion of Antidiuretic Hormone • Diseases of the Parathyroid Glands • Hypoparathyroidism • Primary Hyperparathyroidism • Diseases of the Adrenal Glands • Cushing Syndrome • Pheochromocytoma • Primary Hyperaldosteronism • Adrenal Insufficiency • Congenital Adrenal Hyperplasia
- • 5 DISEASES OF THE CENTRAL AND PERIPHERAL NERVOUS SYSTEMS • Cerebrovascular Disease (Stroke) • Ischemic Stroke (Cerebral Infarction) • Hemorrhagic Stroke • Movement Disorders • Parkinson Disease • Huntington Chorea • Tremor • Ataxia • Restless Leg Syndrome • Tourette Syndrome • Dementia • Overview • Alzheimer Disease • Dementia With Lewy Bodies • Altered Mental Status • Delirium • Coma • Demyelinating Disease • Multiple Sclerosis • Guillain–Barr? Syndrome • Neuromuscular Diseases • Myasthenia Gravis • Duchenne Muscular Dystrophy • Becker Muscular Dystrophy • Neurocutaneous Syndromes • Neurofibromatosis Type I (von Recklinghausen Disease) • Neurofibromatosis Type II • Tuberous Sclerosis • Sturge–Weber Syndrome • Von Hippel–Lindau Disease • Spinal Cord Diseases • Syringomyelia • Brown-S?quard Syndrome • Transverse Myelitis • Horner Syndrome • Poliomyelitis • Miscellaneous Conditions • Vertigo • Syncope • Seizures • Amyotrophic Lateral Sclerosis or “Lou Gehrig Disease” • Aphasia • Bell Palsy • Trigeminal Neuralgia (Tic Douloureux) • How to Localize a Neurologic Lesion
- • 6 CONNECTIVE TISSUE AND JOINT DISEASES • Connective Tissue Diseases • Systemic Lupus Erythematosus • Scleroderma (Systemic Sclerosis) • Sj?gren Syndrome • Mixed Connective Tissue Disease • Rheumatoid Arthritis • Crystal-Induced Arthritides • Gout • Pseudogout (Calcium Pyrophosphate Deposition Disease) • Myopathies and Pain Syndromes • Idiopathic Inflammatory Myopathies • Inclusion Body Myositis • Polymyalgia Rheumatica • Fibromyalgia • Seronegative Spondyloarthropathies • Ankylosing Spondylitis • Reactive Arthritis/Reiter Syndrome • Psoriatic Arthritis • Vasculitis • Vasculitis Overview • Large-Vessel Vasculitides • Medium-Vessel Vasculitides • ANCA-associated Small-Vessel Vasculitides • Immune Complex Small-Vessel Vasculitides • Variable-Vessel Vasculitis
- • 7 DISEASES OF THE RENAL AND GENITOURINARY SYSTEM • Renal Failure • Acute Kidney Injury • Chronic Kidney Disease • Dialysis • Proteinuria and Hematuria • Proteinuria • Hematuria • Glomerular Disease (Glomerulonephropathies) • Overview • Primary Glomerular Disorders • Secondary Glomerular Disorders • Tubulointerstitial Diseases • Acute Interstitial Nephritis • Renal Papillary Necrosis • Renal Tubular Acidosis • Hartnup Syndrome • Fanconi Syndrome • Renal Cystic Diseases • Autosomal Dominant Polycystic Kidney Disease • Autosomal Recessive Polycystic Kidney Disease • Medullary Sponge Kidney • Simple Renal Cysts • Renal Vascular Disease • Renal Artery Stenosis (Renovascular Hypertension) • Renal Vein Thrombosis • Atheroembolic Disease of the Renal Arteries • Hypertensive Nephrosclerosis • Scleroderma • Sickle Cell Nephropathy • Stones and Obstructions • Nephrolithiasis • Urinary Tract Obstruction • Neoplasms • Prostate Cancer • Renal Cell Carcinoma • Bladder Cancer • Testicular Cancer • Penile Cancer • Miscellaneous Conditions • Testicular Torsion • Epididymitis
- • 8 FLUIDS, ELECTROLYTES, AND ACID–BASE DISORDERS • Volume Disorders • Approach to Volume Disorders • Hypovolemia • Hypervolemia • Sodium • Overview of Sodium Homeostasis • Hyponatremia • Hypernatremia • Calcium • Calcium Metabolism • Hypocalcemia • Hypercalcemia • Potassium • Potassium Metabolism • Hypokalemia • Hyperkalemia • Magnesium • Overview • Hypomagnesemia • Hypermagnesemia • Phosphate • Overview • Hypophosphatemia • Hyperphosphatemia • Acid–Base Disorders • Metabolic Acidosis • Metabolic Alkalosis • Respiratory Acidosis • Respiratory Alkalosis
- • 9 HEMATOLOGIC DISEASES AND NEOPLASMS • Anemias • Basics of Anemia • Microcytic Anemias • Iron Deficiency Anemia • Thalassemias • Sideroblastic Anemia • Normocytic Anemias • Anemia of Chronic Disease • Aplastic Anemia • Macrocytic Anemias • Vitamin B12 Deficiency • Folate Deficiency • Hemolytic Anemias • Overview • Sickle Cell Disease • Hereditary Spherocytosis • Glucose-6-Phosphate Dehydrogenase Deficiency • Autoimmune Hemolytic Anemia • Paroxysmal Nocturnal Hemoglobinuria • Platelet Disorders • Thrombocytopenia • Immune (Idiopathic) Thrombocytopenic Purpura • Thrombotic Thrombocytopenic Purpura • Heparin-Induced Thrombocytopenia • Bernard–Soulier Syndrome • Glanzmann Thrombasthenia • Disorders of Coagulation • von Willebrand Disease • Hemophilia A • Hemophilia B • Disseminated Intravascular Coagulation • Vitamin K Deficiency • Coagulopathy of Liver Disease • Hypercoagulable States • Anticoagulation • Heparin • Low–Molecular-Weight Heparin • Warfarin • Direct Oral Anticoagulants (DOACs) or Target-Specific Oral Anticoagulants (TSOACs) • Oncology • Epidemiology • Cancer Prevention and Screening • Principles of Cancer Staging and Therapy • Breast Cancer • Plasma Cell Disorders • Monoclonal Gammopathy of Undetermined Significance • Multiple Myeloma • Waldenstr?m Macroglobulinemia • Lymphomas • Hodgkin Lymphoma • Non-Hodgkin Lymphoma • Leukemias • Acute Leukemias • Chronic Lymphocytic Leukemia • Chronic Myeloid Leukemia • Myeloproliferative Disorders • Polycythemia Vera • Myelodysplastic Syndromes • Essential Thrombocythemia
- • 10 INFECTIOUS DISEASES • Infections of the Upper and Lower Respiratory Tracts • Pneumonia • Ventilator-Associated Pneumonia • Lung Abscess • Tuberculosis • Influenza • Infections of the Central Nervous System • Meningitis • Encephalitis • Infections of the Gastrointestinal Tract • Viral Hepatitis • Botulism • Intra-Abdominal Abscess • Pseudomembranous Colitis • Infections of the Genitourinary Tract • Lower Urinary Tract Infections • Pyelonephritis • Prostatitis • Sexually Transmitted Diseases • Genital Warts • Chlamydia • Gonorrhea • HIV and AIDS • Herpes Simplex • Syphilis • Chancroid • Lymphogranuloma Venereum • Pediculosis Pubis (Pubic Lice) • Wound and Soft Tissue Infections • Cellulitis • Erysipelas • Necrotizing Fasciitis • Lymphadenitis • Tetanus • Infections of the Bones and Joints • Osteomyelitis • Acute Infectious Arthritis • Zoonoses and Arthropod-Borne Diseases • Lyme Disease • Rocky Mountain Spotted Fever • Malaria • Rabies • Other Zoonoses • Common Fungal Infections • Candidiasis • Aspergillus • Cryptococcosis • Other Fungal Infections • Common Parasitic Infections • Fever and Sepsis • Fever of Unknown Origin • Toxic Shock Syndrome • Catheter-Related Sepsis • Neutropenic Fever • Miscellaneous Infections • Infectious Mononucleosis
- • 11 DISEASES OF THE SKIN AND HYPERSENSITIVITY DISORDERS • Key Definitions • Common Skin Disorders • Acneiform Eruptions • Acne Vulgaris • Rosacea • Hidradenitis Suppurativa • Atopic and Contact Dermatitis • Atopic Dermatitis (Eczema) • Contact Dermatitis • Papulosquamous Eruptions • Psoriasis • Seborrheic Dermatitis • Pityriasis Rosea • Lichen Planus • Allergic Reactions • Urticaria (Hives) • Angioedema • Anaphylaxis • Drug Reactions • Other Inflammatory and Autoimmune Disorders • Erythema Nodosum • Pyoderma Gangrenosum • Bullous Pemphigoid • Pemphigus Vulgaris • Vitiligo • Skin Conditions Related to Infections and Infestations • Bacterial Infections • Viral Infections • Warts • Molluscum Contagiosum • Herpes Zoster (Shingles) • Fungal Infections • Dermatophytes • Tinea Versicolor • Infestations • Scabies • Benign and Malignant Skin Lesions • Benign Skin Lesions • Actinic Keratosis (Also Called Solar Keratosis) • Seborrheic Keratosis • Keratoacanthoma • Malignant Skin Lesions • Basal Cell Carcinoma • Squamous Cell Carcinoma • Melanoma
- • 12 AMBULATORY MEDICINE • Cardiovascular Diseases • Hypertension • Hyperlipidemias • Headache • Tension Headache • Cluster Headaches • Migraine • Upper Respiratory Diseases • Cough • Acute Bronchitis • The Common Cold • Sinusitis • Laryngitis • Sore Throat • Gastrointestinal Diseases • Dyspepsia • Gastroesophageal Reflux Disease • Diarrhea • Constipation • Irritable Bowel Syndrome • Nausea and Vomiting • Hemorrhoids • Musculoskeletal Problems • Overview of Musculoskeletal Examination Maneuvers • Low Back Pain • Common Disorders of the Cervical Spine • Knee Pain • Ankle Sprains • Tendinitis and Bursitis • Carpal Tunnel Syndrome • Osteoarthritis • Osteoporosis • Diseases of the Eye • Age-Related Macular Degeneration • Glaucoma • Cataracts • Red Eye • Conjunctivitis • Amaurosis Fugax • Sleep Disorders • Obstructive Sleep Apnea • Narcolepsy • Insomnia • Miscellaneous Topics • Obesity • Hearing Loss/Impaired Hearing • Urinary Incontinence • Fatigue • Erectile Dysfunction • Alcoholism • Smoking • Health Maintenance
- • APPENDIX • Radiographic Interpretation • Chest Radiograph • Abdominal Radiographs • Electrocardiogram Interpretation • Electrocardiogram Pearls • Intravenous Therapy • Central Venous Line • Arterial Lines • Nutritional Support • Guide to Antibacterial Antibiotic Therapy • Physical Examination Pearls • Heart Sounds • Murmurs • Breath Sounds • Abdominal Examination • Neurologic Examination • Tumor Markers • Workup and Management of Common Problems • On The Wards • Hypotension • Hypertension • Chest Pain • Tachycardia • Oliguria • Fever in the Hospitalized Patient • Hypoglycemia • Change in Mental Status (Confusion) • Shortness of Breath/Acute Hypoxia • Basic Statistics and Evidence-Based Medicine • End-of-Life Issues and Informed Consent
- • Questions • Answers • Index
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