Last edition Elsevier Practical, approachable, and perfect for today’s busy medical students and practitioners, BRS Biochemistry, Molecular Biology, and Genetics, Seventh Edition helps ensure excellence in class exams and on the USMLE Step 1. The popular Board Review Series outline format keeps content succinct and accessible for the most efficient review, accompanied by bolded key terms, detailed figures, quick-reference tables, and other aids that highlight important concepts and reinforce understanding.
Last edition
ISBN 13:h9781496399236
Imprint:hLippincott Williams & Wilkins
Language:hEnglish
Authors:hMichael A. Lieberman
Pub Date:h03/2019
Pages:h448
Illus:hIllustrated
Weight:h860.00 grams
Size:h178 x 254 mm
Product Type:hSoftcover
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| grn 1811 |
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- • Updated content keeps students current with the latest clinical approaches to molecular biology, genetics, amino acids, and more.
- • The proven Board Review Series outline format helps students make the most of their study time.
- • Updated Clinical Considerations boxes demonstrate the practical applications of chapter concepts.
- • More than 500 USMLE-style review questions ensure confidence on course exams and the USMLE Step 1.
- • More than 250 high-quality images clarify concepts and clinical details.
- • Chapter overviews, tables, algorithms, and other learning aids save time and simplify the review process.
- • eBook available for purchase. Fast, smart, and convenient, today's eBooks can transform learning. These interactive, fully searchable tools offer 24/7 access on multiple devices, the ability to highlight and share notes, and more
- Michael Lieberman is certified by the American Board of Medical Laboratory Immunology, a qualification for being a High Complexity Laboratory Director by the Centers for Medicare & Medicaid Services. Lieberman is also licensed by the State of Hawaiʻi Department of Health as a Clinical Laboratory Director. Liberman previously served as the laboratory director for Aloha Toxicology Laboratory in Honolulu where he oversaw the successful CLIA Certificate of Compliance process for the lab. Under Libermanʻs leadership, the Aloha Toxicology Lab also expanded services from offering only toxicology screening (FDA approved for IVD) to include confirmatory testing. This expansion required full-scale validations prior to patient testing. Lieberman devised and directed these tests, analyzed resulting data, and developed detailed validation reports. Liberman also served as the laboratory director of the clinical microbiology and immunology sections in the Department of Pathology at the William Beaumont Army Medical Center in El Paso, Texas. In this role Liberman was responsible for all microbiology and immunology clinical specimen testing as well as providing in-service and laboratory based training for pathology residents. He also oversaw the lab’s successful accreditation inspection by the College of American Pathologists (CAP) and established partnerships for clinical research on infectious diseases
- Cover Half Title Page Title Page Copyright Page Preface Acknowledgments How to Use This Book Contents
- 1. Fuel Metabolism and Nutrition: Basic Principles
- Overview I. Metabolic Fuels and Dietary Components II. The Fed or Absorptive State III. Fasting IV. Prolonged Fasting (Starvation) Review Test
- 2. Basic Aspects of Biochemistry: Organic Chemistry, Acid–Base Chemistry, Amino Acids, Protein Structure and Function, and Enzyme Kinetics
- Overview I. A Brief Review of Organic Chemistry II. Acids, Bases, and Buffers III. Amino Acids and Peptide Bonds IV. Protein Structure V. Enzymes Review Test
- 3. Gene Expression (Transcription), Synthesis of Proteins (Translation), and Regulation of Gene Expression
- Overview I. Nucleic Acid Structure II. Synthesis of DNA (Replication) III. Synthesis of RNA (Transcription) IV. Protein Synthesis (Translation of mRNA) V. Regulation of Protein Synthesis VI. Recombinant DNA and Medicine Review Test
- 4. Cell Biology, Signal Transduction, and the Molecular Biology of Cancer
- Overview I. Compartmentation in Cells: Cell Biology and Biochemistry II. Cell Signaling by Chemical Messengers III. The Molecular Biology of Cancer IV. Cancer and Apoptosis V. Cancer Requires Multiple Mutations VI. Viruses and Human Cancer Review Test
- 5. Generation of Atp from Metabolic Fuels and Oxygen Toxicity
- Overview I. Bioenergetics II. Properties of Adenosine Triphosphate III. Electron Carriers and Vitamins IV. Tricarboxylic Acid Cycle V. Electron Transport Chain and Oxidative Phosphorylation VI. Oxygen Toxicity and Free-Radical Injury Review Test
- 6. Carbohydrate Metabolism
- Overview I. Carbohydrate Structure II. Proteoglycans, Glycoproteins, and Glycolipids III. Digestion of Carbohydrates IV. Glycogen Structure and Metabolism V. Glycolysis VI. Gluconeogenesis VII. Fructose and Galactose Metabolism VIII. Pentose Phosphate Pathway IX. Maintenance of Blood Glucose Levels Review Test
- 7. Lipid and Ethanol Metabolism
- Overview I. Lipid Structure II. Membranes III. Digestion of Dietary Triacylglycerol IV. Fatty Acid and Triacylglycerol Synthesis V. Formation of Triacylglycerol Stores in Adipose Tissue VI. Cholesterol and Bile Salt Metabolism VII. Blood Lipoproteins VIII. Fate of Adipose Triacylglycerols IX. Fatty Acid Oxidation X. Ketone Body Synthesis and Utilization XI. Phospholipid and Sphingolipid Metabolism XII. Metabolism of the Eicosanoids XIII. Ethanol Metabolism Review Test
- 8. Nitrogen Metabolism: Amino Acids, Purines, Pyrimidines, and Products Derived from Amino Acids
- Overview I. Protein Digestion and Amino Acid Absorption II. Addition and Removal of Amino Acid Nitrogen III. Urea Cycle IV. Synthesis and Degradation of Amino Acids V. Interrelationships of Various Tissues in Amino Acid Metabolism VI. Tetrahydrofolate, Vitamin B12, and S-Adenosylmethionine VII. Special Products Derived from Amino Acids Review Test
- 9 Molecular Endocrinology and an Overview of Tissue Metabolism
- Overview I. Synthesis of Hormones II. General Mechanisms of Hormone Action III. Regulation of Hormone Levels IV. Actions of Specific Hormones V. Biochemical Functions of Tissues Review Test
- 10. Human Genetics—An Introduction
- Overview I. Mendelian Inheritance Patterns II. Genes III. Mutations IV. Inheritance Patterns V. A Summary of Inheritance Patterns VI. Cytogenetics VII. Population Genetics VIII. Multifactorial Diseases (Complex Traits) IX. Triplet Repeat Expansions X. Imprinting XI. Epigenetics XII. The Genetics of Tumor Suppressors XIII. Metabolic Genetic Disorders Involving Carbohydrate and Lipid Pathways Review Test Comprehensive Examination Index
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