Last edition Elsevier Gain a full understanding of the principles of biochemistry as it relates to clinical medicine The Thirty-First Edition of Harper’s Illustrated Biochemistry continues to emphasize the link between biochemistry and the understanding of disease states, disease pathology, and the practice of medicine. Featuring a full-color presentation and numerous medically relevant examples, Harper’s presents a clear, succinct review of the fundamentals of biochemistry that every student must understand in order to succeed in medical school. All 58 chapters help you understand the medical relevance of biochemistry: *Full-color presentation includes more than 600 illustrations*Case studies emphasize the clinical relevance of biochemistry *NEW CHAPTER on Biochemistry of Transition Metals addresses the importance and overall pervasiveness of transition metals*Review Questions follow each of the eleven sections*Boxed Objectives define the goals of each chapter*Tables encapsulate important information*Every chapter includes a section on the biomedical importance of a given topic Applauded by medical students and online reviewers for its currency and engaging style, Harper’s Illustrated Biochemistry is essential for USMLE (R) review and the single-best reference for learning the clinical relevance of any biochemistry topic.
Last Edition
ISBN 13:h9781259837937
Imprint:hMcGraw-Hill Education
Language:hEnglish
Authors:hVictor W. Rodwell
Pub Date:h05/2018
Pages:h800
Illus:hIllustrated
Weight:h1,590.000 grams
Size:h216 X 274 mm
Product Type:hSoftcover
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- • Full-color presentation includes more than 600 illustrations
- • Case studies emphasize the clinical relevance of biochemistry
- • NEW CHAPTER on Biochemistry of Transition Metals addresses the importance and overall pervasiveness of transition metals
- • Review Questions follow each of the eleven sections
- • Boxed Objectives define the goals of each chapter
- • Tables encapsulate important information
- • Every chapter includes a section on the biomedical importance of a given topic
- • Emphasis throughout on the integral relationship between biochemistry and disease, diagnostic pathology, and medical practice
- • Hundreds of references to disease states throughout
- • New chapter addressing the biochemical roles of transition metals
- • Many updated review questions
- • Frequent tables summarizing key links to disease states
- • New text on cryo-electron microscopy (cryo-EM)
- • Cover picture of the protein structure of the Zika virus, solved by cryo-EM
- Victor W. Rodwell, PhD (West Lafayette, IN), Professor (Emeritus) of Biochemistry, Purdue University, West Lafayette, Indiana.
- David A. Bender, PhD (London, UK) Professor (Emeritus) of Nutritional Biochemistry, University College London, London, United Kingdom.
- Kathleen M. Botham, PhD, DSc, (London, UK) Professor of Biochemistry, Department of Comparative Biomedical Sciences, Royal Veterinary College, University of London, London, United Kingdom.
- Kennelly, PhD (Blacksburg, VA), Professor and Head, Department of Biochemistry, Virginia Tech, Blacksburg, Virginia.
- P. Anthony Weil, PhD (Nashville, TN), Professor, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, Tennessee.
- Section I: Structures & Functions of Proteins & Enzymes
- Chapter 1: Biochemistry & Medicine o Chapter 2: Water & pH o Chapter 3: Amino Acids & Peptides o Chapter 4: Proteins: Determination of Primary Structure o Chapter 5: Proteins: Higher Orders of Structure
- Section II: Enzymes: Kinetics, Mechanism, Regulation, & Role of Transition Metals
- Chapter 6: Proteins: Myoglobin & Hemoglobin o Chapter 7: Enzymes: Mechanism of Action o Chapter 8: Enzymes: Kinetics o Chapter 9: Enzymes: Regulation of Activities o Chapter 10: The Biochemical Roles of Transition Metals
- Section III: Bioenergetics
- Chapter 11: Bioenergetics: The Role of ATP o Chapter 12: Biologic Oxidation o Chapter 13: The Respiratory Chain & Oxidative Phosphorylation
- Section IV: Metabolism of Carbohydrates
- Chapter 14: Overview of Metabolism & the Provision of Metabolic Fuels o Chapter 15: Carbohydrates of Physiological Significance o Chapter 16: The Citric Acid Cycle: The Central Pathway of Carbohydrate, Lipid, & Amino Acid Metabolism o Chapter 17: Glycolysis & the Oxidation of Pyruvate o Chapter 18: Metabolism of Glycogen o Chapter 19: Gluconeogenesis & the Control of Blood Glucose o Chapter 20: The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism
- Section V: Metabolism of Lipids
- Chapter 21: Lipids of Physiologic Significance o Chapter 22: Oxidation of Fatty Acids: Ketogenesis o Chapter 23: Biosynthesis of Fatty Acids & Eicosanoids o Chapter 24: Metabolism of Acylglycerols & Sphingolipids o Chapter 25: Lipid Transport & Storage o Chapter 26: Cholesterol Synthesis, Transport, & Excretion
- Section VI: Metabolism of Proteins & Amino Acids
- Chapter 27: Biosynthesis of the Nutritionally Nonessential Amino Acids o Chapter 28: Catabolism of Proteins & of Amino Acid Nitrogen o Chapter 29: Catabolism of the Carbon Skeletons of Amino Acids o Chapter 30: Conversion of Amino Acids to Specialized Products o Chapter 31: Porphyrins & Bile Pigments
- Section VII: Structure, Function, & Replication of Informational Macromolecules
- Chapter 32: Nucleotides o Chapter 33: Metabolism of Purine & Pyrimidine Nucleotides o Chapter 34: Nucleic Acid Structure & Function o Chapter 35: DNA Organization, Replication, & Repair o Chapter 36: RNA Synthesis, Processing, & Modification o Chapter 37: Protein Synthesis & the Genetic Code o Chapter 38: Regulation of Gene Expression o Chapter 39: Molecular Genetics, Recombinant DNA, & Genomic Technology
- Section VIII: Biochemistry of Extracellular & Intracellular Communication
- Chapter 40: Membranes: Structure & Function o Chapter 41: The Diversity of the Endocrine System o Chapter 42: Hormone Action & Signal Transduction
- Section IX: Special Topics (A)
- Chapter 43: Nutrition, Digestion, & Absorption o Chapter 44: Micronutrients: Vitamins & Minerals o Chapter 45: Free Radicals & Antioxidant Nutrients o Chapter 46: Glycoproteins o Chapter 47: Metabolism of Xenobiotics o Chapter 48: Clinical Biochemistry
- Section X: Special Topics (B)
- Chapter 49: Intracellular Traffic & Sorting of Proteins o Chapter 50: The Extracellular Matrix o Chapter 51: Muscle & the Cytoskeleton o Chapter 52: Plasma Proteins & Immunoglobulins o Chapter 53: Red Blood Cells o Chapter 54: White Blood Cells
- Section XI: Special Topics (C)
- Chapter 55: Hemostasis & Thrombosis o Chapter 56: Cancer: An Overview o Chapter 57: The Biochemistry of Aging o Chapter 58: Biochemical Case Histories
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